Game Notes
- Release date: August 8, 2005 (Based on the 2005 NFL season.)
- Cover athlete: Donovan McNabb QB Philadelphia Eagles (GameCube, Nintendo DS, PS2, PSP, Xbox, Xbox 360, Windows PC, Mobile phone)
Player Notes
- 99 Overall Club: QB Peyton Manning (Colts), WR Randy Moss (Raiders), LT Jonathan Ogden (Ravens), MLB Ray Lewis (Ravens), K Adam Vinatieri (Patriots), K David Akers (Eagles)